Diabetic Retinopathy

A wholesome medicine to treat diabetic retinopathy & complications and improve quality of life.
Diabetic retinopathy is a serious complication of diabetes that affects the blood vessels in the retina, the light-sensitive tissue at the back of the eye responsible for vision.
Over time, high blood sugar levels damage these tiny blood vessels, leading to leakage, swelling, and impaired blood flow. If left unmanaged, this condition can progress to vision loss or even blindness.

Current scenario of diabetic retinopathy management (DR)

Diabetic Retinopathy: A primary cause of vision loss in adults aged 20-74 years

Amongst the approx. 422 million people with diabetes mellitus worldwide, 35% (145 million) have form DR *1
1.06% of blindness world-wide could be attributed to DR *2
11% (45 million) have vision-threatening DR *3

*1- Lee et al, 2015, Ting et al; 2016, Yau et al; 2012

*2- Flaxman et al; 2017

*3- Lee et al, 2015, Yau et al, 2012

Current solutions and practices

Argon-laser photocoagulation

Anti-VEGF injections

Intravitreal corticosteroids

Vitreoretinal surgery

Limitations of current solutions (Nentwich & Ulbig):

Adverse reactions associated with medication:

1. Vision loss, scar, bleeding in the eye, Reduced colored vision.

2. Elevated intra-ocular pressure (glaucoma).

3. Cataract formation.

4. Recurrent hemorrhage.

5. Retinal detachment.

Adverse reaction associated with route of administration:

1. Endophthalmitis.

2. Vitreous hemorrhage.

3. Retinal detachment.

4. Eye irritation/discomfort.

5. Floaters or feeling of having something in eye.

6. Watery or dry itchy eyes.

7. Scar formed from treatment.

A study was conducted by administration of Trinetra Atibala for 90 days and below is the Optical coherence tomography (OCT) images to show changes in macular edema observed after 90 treatment